Main Street Pizzeria

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213 W Main St
Pickens, SC 29671

Phone: (864) 898-4200

Neighborhood: Pickens

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Popular Menu Items

• Bay Fries
• Crispy boardwalk fries coated in bay seasoning and served with a side of cheese wiz.
• Zucchini Planks
• NEW! Housemade, served with a side of marinara.
• 1 Cheese Steak Eggroll
• Now sold individually! One Crispy Eggroll stuffed with steak & american cheese. Served with a side of sriracha ketchup
• Chicken Strips
• Cripsy chicken strips, served with a choice of bbq, honey mustard, or ranch sauce.
• Everything Garlic Knots
• 4 Delicious Garlic Knots Tossed in Fresh Garlic, Olive Oil & Everything Seasoning!

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Restaurant Description

Main street pizza offers fresh made pizzas, wings, and subs using quality ingredients, fresh made dough, and fresh made sauce daily.

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Reviews for Main Street Pizzeria

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  4.4 stars - Based on 55 reviews

#29 out of 55 restaurants in Pickens

#2 of 5 Pizza in Pickens

5 star				36 reviews	65%
4 star				12 reviews	22%
3 star				4 reviews	7%
2 star				1 review	2%
1 star				2 reviews	4%

Top Reviews of Main Street Pizzeria

02/20/2025 - Joanie Y.
The wings here are consistently impressive, and the pizza is also worth mentioning. I enjoyed a large mushroom, hamburger, and olive pizza that was exceptional, and my husband, who typically doesn't favor pizza, was surprised by how much he liked it. While the food quality is excellent, the restaurant's cleanliness leaves something to be desired, but the friendly staff and great service make up for it.

05/10/2024 - Ophelia O.
AWESOME!

11/21/2023 - Ava dionne
Best pizza place in pickens

04/28/2023 - Barbara
Very awesome Hot and Fresh every time Highly recommend ☺️☺️

04/05/2023 - Lisa
Their food is really good and every time it is fresh the delivery person is so nice I have enjoyed the food so many times 🥳😊

04/05/2023 - Tamy Keeney
Amazingly good food and pizza worth the money! Get yourself some!

01/13/2023 - Barbara
Every time that I have ordered from here which has been a lot over 14 years it is always quick hot and fresh and very delicious

10/02/2022 - Kathy
Great food and service.

07/23/2022 - Melanie
Great customer service! We finally found a place that delivers to Six Mile. We will definitely be ordering again.

06/20/2022 - Jean Eades
Great teriyaki wings!

03/11/2022 - Diane Saint
Best thin crust in Pickens and Easley! Really enjoyed it, will order again and again. Ordered the Peanut Butter Pie. Although it was good I could not taste peanut butter. My husband ordered the Chocolate Pie and he really enjoyed it.

02/21/2022 - Debra
I've never had a bad experience here. Customer service, delivery, and food are all spot on. Also, I can FINALLY get a pizza delivered to Six Mile!!!

01/31/2022 - Laurie
We have been ordering from Main Street Pizza for a long time. Normally it is really good, but the quality has been going down for several months. When you spend $40-50 plus delivery fee and tip on Pizza. It had better be really good. The confirmation email said it would be here in 45 minutes, It took over an hour. The driver said he had a delivery before ours. By the time we got it. The pizza was COLD!! THIS WAS THE WORST PIZZA WE EVER GOT!! If I wanted cold pizza, I would have taken it out of my freezer. We didn't even didn't even finish one slice each, I took 1 bite. The cheesy bread was better than the pizza, but it was COLD, too. I don't think I will order from them again. This is the 2nd time in a row that we got bad pizza there. It used to be the BEST pizza in town. NOW, NOT ONLY ARE THEY THE MOST EXPENSIVE IN TOWN, THEY ARE THE WORST IN TOWN!!!

10/15/2021 - Tom
Best thin crust pizza and wings in the upstate.

09/22/2021 - Sandy Gardner
We love the garlic Parmesan wings and the pizza we ordered was ready when they said ! I highly recommend you try this place!!

08/01/2021 - Carol Trotter
The best pizza and salads!

10/27/2020 - PaulNKrista
Thank GOD this place is here in this lame town and that I love their PIZZA! Since losing my wife recently, I would starve if not fo MSPizza and NEVER WAIT LONG at all. Nice Drivers and hopefully they are taking care of staff who after delivering pizza and/or truckng for 20 years I kmow how vital and important drivers are to buisness and profits. Thanks for the lunch and dinners everyone! Matter of FACT...I am calling now for some good eatz!

09/01/2020 - TJHank
I order a calzone with extra 3í— ricotta it looked like and cutting it open didn't look to have any real extra amount of ricotta it is not a calzone it's a pizza roll

05/10/2017 - Liz
recently re-located from NYC and had not found any pizza I would eat again. Tried Main Street on a whim and was happily shocked. Ordered the thin crust pie and it was delicious. Very polite people on the phones and a really nice delivery person. Have to say this Pizza is much better than Joe's NY Pizza in Seneca. We are so happy we found Main Street and will be regular customers going forward

09/18/2015 - Adam youngblood
Pizza was great but terrible service when I called for delivery. Very poor service attitude

12/28/2014 - Moneymaker
Great pie and the price is right too!

10/24/2014 - Sheila Miller
Awesome pizza guys.. Love it!!

05/13/2009 - Cayce Franklin
Great pizza, but the lasgna is the BEST!